KEGG   REACTION: R02501
Entry
R02501                      Reaction                               
Name
testosterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (19-hydroxylating)
Definition
Testosterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Hydroxytestosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C00535 + C03024 + C00007 <=> C05294 + C03161 + C00001
Comment
aromatase, ARO
three successive reactions (R02501+R04761+R03087)
subsequently R04761
Reaction class
RC00257  C00535_C05294
Enzyme
1.14.14.14
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.14
     R02501  Testosterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 19-Hydroxytestosterone + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K07434  aromatase [EC:1.14.14.14]
Other DBs
RHEA: 38182

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (537)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (536)   
All databases (550)   

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